Several studies have scientifically proven that people who have good virological control of HIV with antiretroviral treatment do not transmit the virus sexually, Undetectable=Untransmittable (I=I). Therefore, early diagnosis of infection is very important so that treatment can be started as early as possible to prevent further transmission ...
The pursuit of an HIV cure faces significant challenges, including the central role of CD4+T cells in the initial immune response, the rapid establishment of latent infection in multiple tissues, and the development of resistance mechanisms in infected cells ...
Curing HIV infection remains a very relevant issue because people with HIV have long-term complications related to the infection, therapy, and stigma. We review the challenges faced by participants and healthcare professionals participating in clinical research trials related to the HIV Cure ...
Extracellular vesicles are involved in several pathological processes, including HIV infection. These processes include the transport of pro-inflammatory cytokines, which are key modulators of the inflammatory response. Specific EV-associated cytokines have been identified as biomarkers of HIV infection status ...
Antiretroviral therapy (ART) effectively controls HIV replication but cannot eliminate the viral reservoir. However, as time with ART progresses, the reservoir appears to change and become enriched in defective proviruses that do not produce new viruses ...
The human immunodeficiency virus (HIV) can progressively destroy the host's immune system. However, thanks to advances in scientific knowledge, for years we have had a highly effective treatment to control the infection and prevent immune deterioration, so that HIV has become a chronic infection, rather than a fatal one ...
