Loss of muscle strength is a prevalent and clinically relevant functional impairment in people with cancer, associated with sarcopenia and early functional limitations. Current evidence identifies muscle strength (handgrip and lower-limb strength) as an independent predictor of mortality, treatment tolerance, and quality of life ...
Cancer incidence increases with age across most oncological diagnoses, and older adults with cancer present a high prevalence of multimorbidity, sarcopenia, and functional decline, which may be exacerbated by the accelerated aging effects associated with cancer treatments ...
Musculoskeletal pain is a prevalent condition in the general population, representing a leading cause of disability, reduced quality of life, and associated economic loss. Approximately one in two European adults suffers from some form of musculoskeletal pain each year; low back pain accounts for 46% of cases annually, while neck and upper-limb pain account for 44% ...
Breast cancer (BC) survivors have a significantly higher risk of cardiovascular disease than the general population. Peak oxygen uptake (VO₂peak) is considered the "fifth vital sign" and a critical predictor of mortality. However, during cancer treatment, it may decline by 5% to 26% ...
Anterior cruciate ligament (ACL) reconstruction is one of the most significant injuries in sports due to its high reinjury rates and the complexity of the return-to-sport process. Traditionally, Return-to-Play (RTP) decisions have been based primarily on time-based criteria; however, current scientific evidence supports multifactorial models incorporating clinical, functional, psychological, and sport-specific indicators ...
